Psoriasis is a long-term skin disease that causes red, scaly, itchy patches on the body. When creams, ointments, or tablets do not work well, biological treatments (biologics) provide excellent and long-lasting relief.
If you are searching for a psoriasis treatment in Chennai, this guide will help you understand the latest biological treatments for psoriasis and how they can control the disease safely.

How are Biologicals used in Psoriasis Treatment?
Biologicals are advanced injectable medicines that treat psoriasis by targeting the exact immune signals that cause skin inflammation.
Unlike older medicines, biologics:
Act precisely on the disease
Have fewer long-term side effects
Provide better skin clearance
They are prescribed by an experienced dermatologists treating psoriasis in Chennai, after proper evaluation and blood tests.
Types of Biologicals Available for Psoriasis treatment
1. TNF-Alpha Inhibitors
These were the first biological medicines used for psoriasis.
Common options include:
Adalimumab
Etanercept
Infliximab
Who benefits most
Patients with psoriasis and joint pain
Patients needing faster improvement
Limitations
Slightly higher infection risk
Newer biologics are more effective for skin clearance
2. IL-12 / IL-23 Inhibitor
Ustekinumab
Why it is popular
Injection once every 3 months
Good safety record
Effective for skin and joints
This option is commonly chosen by patients visiting a psoriasis clinic who prefer fewer injections.
3. IL-17 Inhibitors – Fast Results
These biologics clear psoriasis very quickly, often within weeks.
Available IL-17 biologics:
Secukinumab
Ixekizumab
Brodalumab
Best for
Severe plaque psoriasis
Scalp, nail, palm, and sole psoriasis
Patients wanting rapid improvement
4. IL-23 Inhibitors – Latest & Most Advanced
These are the most advanced biological treatments available today.
Common IL-23 inhibitors:
Guselkumab
Risankizumab
Tildrakizumab
Why dermatologists prefer them
Excellent long-term skin clearance
Very low infection risk
Injections once every 8–12 weeks
Ideal for long-term psoriasis control
Many patients achieve clear or almost clear skin with these medicines.
How a Dermatologist chooses the Right Biologic for psoriasis treatment
The best treatment is chosen based on:
Severity of psoriasis
Presence of psoriatic arthritis
Age and lifestyle
Previous treatments
Other medical conditions
Cost and availability in Chennai
Before starting treatment, patients undergo:
Blood tests
Infection screening
Regular follow-ups for safety
Are Biologicals Safe for Long-Term Use?
Yes. When prescribed by an experienced dermatologist, biologics are usually well-tolerated.
Most patients experience:
Significant reduction in itching and scaling
Better sleep and confidence
Improved quality of life
When Should You See a Dermatologist for psoriasis treatment?
You should consult a specialist if:
Psoriasis is spreading or worsening
Creams and tablets are not working
You have joint pain with psoriasis
Severe scalp, nail, or palm-sole involvement
Frequent relapses affecting daily life
Expert Psoriasis Treatment in Chennai
Biological therapy has revolutionised psoriasis treatment. With expert care and the right biologic, long-term control is now achievable.
If you are looking for a trusted psoriasis doctor in Chennai, consult a dermatologist experienced in biological therapy for psoriasis.
