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Role of Biologicals in Psoriasis treatment

Dec 21, 2025

2 min read

Psoriasis is a long-term skin disease that causes red, scaly, itchy patches on the body. When creams, ointments, or tablets do not work well, biological treatments (biologics) provide excellent and long-lasting relief.


If you are searching for a psoriasis treatment in Chennai, this guide will help you understand the latest biological treatments for psoriasis and how they can control the disease safely.


Biologicals in psoriasis treatment Chennai

How are Biologicals used in Psoriasis Treatment?


Biologicals are advanced injectable medicines that treat psoriasis by targeting the exact immune signals that cause skin inflammation.


Unlike older medicines, biologics:

  • Act precisely on the disease

  • Have fewer long-term side effects

  • Provide better skin clearance


They are prescribed by an experienced dermatologists treating psoriasis in Chennai, after proper evaluation and blood tests.


Types of Biologicals Available for Psoriasis treatment


1. TNF-Alpha Inhibitors


These were the first biological medicines used for psoriasis.


Common options include:

  • Adalimumab

  • Etanercept

  • Infliximab


Who benefits most

  • Patients with psoriasis and joint pain

  • Patients needing faster improvement


Limitations

  • Slightly higher infection risk

  • Newer biologics are more effective for skin clearance


2. IL-12 / IL-23 Inhibitor


  • Ustekinumab


Why it is popular

  • Injection once every 3 months

  • Good safety record

  • Effective for skin and joints


This option is commonly chosen by patients visiting a psoriasis clinic who prefer fewer injections.


3. IL-17 Inhibitors – Fast Results


These biologics clear psoriasis very quickly, often within weeks.


Available IL-17 biologics:

  • Secukinumab

  • Ixekizumab

  • Brodalumab


Best for

  • Severe plaque psoriasis

  • Scalp, nail, palm, and sole psoriasis

  • Patients wanting rapid improvement


4. IL-23 Inhibitors – Latest & Most Advanced


These are the most advanced biological treatments available today.


Common IL-23 inhibitors:

  • Guselkumab

  • Risankizumab

  • Tildrakizumab


Why dermatologists prefer them


  • Excellent long-term skin clearance

  • Very low infection risk

  • Injections once every 8–12 weeks

  • Ideal for long-term psoriasis control


Many patients achieve clear or almost clear skin with these medicines.


How a Dermatologist chooses the Right Biologic for psoriasis treatment


The best treatment is chosen based on:

  • Severity of psoriasis

  • Presence of psoriatic arthritis

  • Age and lifestyle

  • Previous treatments

  • Other medical conditions

  • Cost and availability in Chennai


Before starting treatment, patients undergo:

  • Blood tests

  • Infection screening

  • Regular follow-ups for safety


Are Biologicals Safe for Long-Term Use?

Yes. When prescribed by an experienced dermatologist, biologics are usually well-tolerated.


Most patients experience:

  • Significant reduction in itching and scaling

  • Better sleep and confidence

  • Improved quality of life


When Should You See a Dermatologist for psoriasis treatment?


You should consult a specialist if:

  • Psoriasis is spreading or worsening

  • Creams and tablets are not working

  • You have joint pain with psoriasis

  • Severe scalp, nail, or palm-sole involvement

  • Frequent relapses affecting daily life


Expert Psoriasis Treatment in Chennai


Biological therapy has revolutionised psoriasis treatment. With expert care and the right biologic, long-term control is now achievable.


If you are looking for a trusted psoriasis doctor in Chennai, consult a dermatologist experienced in biological therapy for psoriasis.

Dec 21, 2025

2 min read

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